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[免疫球蛋白在感染性过敏性支气管哮喘中的诊断意义]

[Diagnostic significance of immunoglobulins in infectious allergic bronchial asthma].

作者信息

Zheltvaĭ V V, Kazankevich V P, Chekotilo V M, Valkovtsi A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1981 Nov(11):84-9.

PMID:6459694
Abstract

In 100 patients with infectious allergic bronchial asthma the levels of IgM. IgG and IgA were determined by Mancini's method and the levels of IgE, tissue and microbial antibodies by the Prausnitz - Küstner test before and after combined treatment carried out under conditions of the microclimate of the salt mines in the village of Solotvino. The data on the content of immunoglobulins in the blood serum allowed the authors to establish 3 types of immediate hypersensitivity. THe decreased content of IgM in the blood serum indirectly revealed the role of immune complexes in the pathogenesis of infectious allergic bronchial asthma. The high content of IgE suggested that atopy could take some part in the infectious process.

摘要

对100例感染性过敏性支气管哮喘患者,在索洛特维诺村盐矿小气候条件下进行联合治疗前后,采用曼西尼法测定IgM、IgG和IgA水平,采用普劳斯尼茨-屈斯特纳试验测定IgE、组织抗体和微生物抗体水平。血清免疫球蛋白含量的数据使作者能够确定3种速发型超敏反应类型。血清中IgM含量降低间接揭示了免疫复合物在感染性过敏性支气管哮喘发病机制中的作用。IgE含量高表明特应性可能在感染过程中起一定作用。

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