Lagneaux D, Lecomte J, Remacle R
C R Seances Soc Biol Fil. 1981;175(6):889-94.
High concentrations (FiCO2 0.3) of carbon dioxide in the inspired air provoke acute pulmonary oedema in the vagotomized rats only, the animals dying of acute asphyxia in a few minutes. Vagotomy accelerates the production of pulmonary transudates mainly by increasing capillary-alveolar transmural pressure: tidal volume and pleural depression are largely augmented after stimulation of the respiratory centers by CO2.
仅在迷走神经切断的大鼠中,吸入空气中高浓度(二氧化碳分数0.3)的二氧化碳会引发急性肺水肿,动物在几分钟内死于急性窒息。迷走神经切断主要通过增加毛细血管-肺泡跨壁压力来加速肺渗出液的产生:在二氧化碳刺激呼吸中枢后,潮气量和胸膜凹陷会大幅增加。