线粒体腺苷三磷酸酶蛋白抑制剂的氨基酸序列。
Amino acid sequence of the protein inhibitor of mitochondrial adenosine triphosphatase.
作者信息
Frangione B, Rosenwasser E, Penefsky H S, Pullman M E
出版信息
Proc Natl Acad Sci U S A. 1981 Dec;78(12):7403-7. doi: 10.1073/pnas.78.12.7403.
Abstract
The complete amino acid sequence of the mitochondrial ATPase inhibitor peptide was determined. The molecule contains 84 residues of which 40 are charged amino acids that occur in clusters along the chain. A section of the chain, located at the COOH-terminal end, contains several duplicated regions, the most prominent of which are pentapeptides. This section of the chain also contains all of the five histidines present in the molecule. Some of the physicochemical properties of the protein and an improved purification procedure are described.
摘要
确定了线粒体ATP酶抑制剂肽的完整氨基酸序列。该分子含有84个残基，其中40个是带电荷的氨基酸，它们沿链成簇出现。位于COOH末端的一段链包含几个重复区域，其中最突出的是五肽。该链段还包含分子中存在的所有五个组氨酸。描述了该蛋白质的一些物理化学性质以及一种改进的纯化方法。
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