Thumann A, Bustos-Obregón E
Andrologia. 1982 Jan-Feb;14(1):35-40, 42. doi: 10.1111/j.1439-0272.1982.tb03093.x.
The spermatogonial chalone activity is analyzed in correlation to the germinal cell population present in the seminiferous tubules of prepuberal rats. The assay is done in an "in vitro" system and aims at identifying the cell type that produces the chalone. It was found that the spermatogonial chalone is produced by the germinal cells, its production increases with the age of the animals and attains its maximum in 40 days old rats. There is a direct relationship between the amount of chalone produced and the number of spermatocytes present in the seminiferous tubules of prepuberal rats. The response of the germ cells to the chalone is maximal by 25 days of age. The apparent decrease of response in 40 days old rats may be related to the establishment of a complete germ cell line.
分析青春期前大鼠生精小管中存在的生殖细胞群体与精原细胞抑素活性的相关性。该测定在“体外”系统中进行，旨在鉴定产生抑素的细胞类型。研究发现，精原细胞抑素由生殖细胞产生，其产生量随动物年龄增加而增加，并在40日龄大鼠中达到最大值。青春期前大鼠生精小管中产生的抑素量与存在的精母细胞数量之间存在直接关系。生殖细胞对抑素的反应在25日龄时最大。40日龄大鼠中反应的明显下降可能与完整生殖细胞系的建立有关。
