Förström L, Lassus A, Salde L, Niemi K M
Contact Dermatitis. 1982 Mar;8(2):128-33. doi: 10.1111/j.1600-0536.1982.tb04158.x.
Epicutaneous tests with topical steroids in therapeutic and ten-fold therapeutic concentrations in ethanol were performed in 105 patients selected on the basis of unresponsiveness of their eczema to topical corticosteroids or because topical steroids had provoked eczema around treated psoriatic lesions. Five patients showed allergic test reactions to one or several steroids. One of the two clobetasol-17-propionate sensitive patients reacted to the weak concentration only. The problem related to the instability of many steroids in ethanolic solution is discussed. After one month of storage in a refrigerator, the chromatographic purity of several test substances fell to 95-75%.
对105名患者进行了乙醇中治疗浓度及十倍治疗浓度的外用类固醇皮肤试验，这些患者要么是湿疹对外用皮质类固醇无反应，要么是外用类固醇引发了银屑病皮损周围的湿疹。5名患者对一种或几种类固醇出现过敏试验反应。两名对丙酸氯倍他索敏感的患者中，有一名仅对低浓度有反应。讨论了许多类固醇在乙醇溶液中不稳定的问题。在冰箱中储存一个月后，几种测试物质的色谱纯度降至95%-75%。
