Osmundsen P E
Contact Dermatitis. 1982 Mar;8(2):81-3. doi: 10.1111/j.1600-0536.1982.tb04150.x.
In a 3-year period, 551 patients were patch tested with chlorhexidine gluconate 1% in water. 14 patients showed a strong and obviously relevant reaction. A severe dermatitis developed during treatment with a chlorhexidine preparation in 10 patients with venous or traumatic ulcers of the leg, and in 4 patients with skin infection on the face and/or scalp. So far the sensitizing potential of chlorhexidine has probably been underestimated.
在3年期间，551名患者接受了1%葡萄糖酸洗必泰水溶液的斑贴试验。14名患者出现强烈且明显相关的反应。10名患有腿部静脉或创伤性溃疡的患者以及4名面部和/或头皮皮肤感染的患者在使用洗必泰制剂治疗期间发生了严重皮炎。到目前为止，洗必泰的致敏潜力可能被低估了。
