Hollmen A I, Jouppila R, Koivisto M, Maatta L, Pihlajaniemi R, Puukka M, Rantakyla P
Anesthesiology. 1978 May;48(5):350-6. doi: 10.1097/00000542-197805000-00009.
Elective cesarean section was performed in a consecutive series of 30 patients with full-term pregnancies who were not in labor. Epidural (lidocaine, 1.5 per cent, with epinephrine, 1:200,000) and general anesthesia (thiopental, nitrous oxide-oxygen, succinylcholine infusion) was used alternately. Neonatal acid-base values and Apgar scores showed no significant difference between the two anesthetic groups, and most infants were vigorous at birth. The neurologic recoveries of the infants showed no significant difference between the two groups. In the group receiving epidural anesthesia, there was a significant correlation between maternal hypotension and weak rooting and sucking reflexes of the infants during the first two days. All infants of high-risk obstetric patients in the series, independent of anesthetic technique used, had abnormal neurologic activity, as evidenced by either depression of muscle tone and the reflexes or all the tested variables. Neurologic assessment as followed in this series is a sensitive indicator of the effects of fetal stress factors acting during cesarean section.
对连续30例足月未临产孕妇进行了选择性剖宫产。交替使用硬膜外麻醉(1.5%利多卡因加1:200,000肾上腺素)和全身麻醉(硫喷妥钠、氧化亚氮-氧气、琥珀酰胆碱输注)。两组麻醉方式下新生儿的酸碱值和阿氏评分无显著差异,且大多数婴儿出生时情况良好。两组婴儿的神经功能恢复情况无显著差异。在接受硬膜外麻醉的组中,产妇低血压与婴儿出生后头两天较弱的觅食和吸吮反射之间存在显著相关性。该系列中所有高危产科患者的婴儿,无论采用何种麻醉技术,均有异常的神经活动,表现为肌张力和反射降低或所有测试变量异常。本系列中所采用的神经功能评估是剖宫产期间胎儿应激因素影响的敏感指标。