Storozhuk V M, Ivanova S F, Tal'nov A N
Neirofiziologiia. 1984;16(3):403-19.
The conditional placing reflex was studied in chronic experiments on cats. Neuronal activity of the midbrain periaqueductal grey matter was recorded under conditions of extinction, differentiation and conditional inhibition. Neuronal reactions preceded the conditioned and voluntary movements by 400-800 ms and lasted for 1-2 s in 69 units from total numbers 182 (36.7%). This reactions appeared 200 ms earlier than corresponding neuronal reactions of the motor cortex. 58 neurons (30.9%) were excited by auditory stimuli with latencies 10-50 ms for 2-6 s. 19 neurons (10.1%) were activated by auditory stimuli and conditioned movement. Responses to isolated auditory stimulation were absent in 42 neurons (22.3%), but some of the neurons showed long-lasting (minutes) changes of the background activity under repeated conditioned stimulation. The extinction, differentiation and conditioned inhibition caused specific changes in activity of different neuronal groups. A conclusion is made that the periaqueductal grey matter participated in reflex performance as well as in its inhibition. The functional independence of the first and second neuronal groups in extinction and restoration of conditional reflex is shown.
在对猫进行的慢性实验中研究了条件性放置反射。在消退、分化和条件抑制的条件下记录中脑导水管周围灰质的神经元活动。在总共182个单位中有69个单位（36.7%）的神经元反应在条件性和自主性运动之前400 - 800毫秒出现，并持续1 - 2秒。这种反应比运动皮层相应的神经元反应早200毫秒出现。58个神经元（30.9%）在10 - 50毫秒的潜伏期内被听觉刺激兴奋2 - 6秒。19个神经元（10.1%）被听觉刺激和条件性运动激活。42个神经元（22.3%）对孤立的听觉刺激没有反应，但其中一些神经元在重复的条件刺激下表现出背景活动的长期（数分钟）变化。消退、分化和条件抑制导致不同神经元组的活动发生特定变化。得出的结论是，导水管周围灰质既参与反射表现也参与其抑制。显示了第一和第二神经元组在条件反射消退和恢复中的功能独立性。
