Luesley D M, Chan K K, Fielding J W, Hurlow R, Blackledge G R, Jordon J A
Obstet Gynecol. 1984 Sep;64(3):421-6.
Fifty patients with ovarian cancer had a second-look laparotomy performed after chemotherapy. Complete histologic response was confirmed in 12 patients, microscopic disease was found in 12 patients, and macroscopic disease was found in 26 patients. Fifteen patients with macroscopic disease had total tumor clearance at second look. Surgical response to chemotherapy was found to correlate well with disease volume at the onset of chemotherapy. The operation is a safe, accurate technique for assessing the ovarian cancer patient. The findings and outcome probably depend upon the timing of the procedure. Any survival benefit from the operation remains to be proved.
50例卵巢癌患者在化疗后接受了二次剖腹探查术。12例患者确认有完全组织学缓解，12例发现有微小病灶，26例发现有肉眼可见病灶。15例有肉眼可见病灶的患者在二次探查时实现了肿瘤完全清除。发现手术对化疗的反应与化疗开始时的疾病体积密切相关。该手术是评估卵巢癌患者的一种安全、准确的技术。其结果可能取决于手术时机。该手术对生存的任何益处仍有待证实。
