Zommer-Urbańska S, Urbańska J
Pol J Pharmacol Pharm. 1984 Jan-Feb;36(1):13-8.
Electronic spectra of butobendin are stable between pH 1.00 and 10.89, but they change with pH in the range 10.89-2.19, due to hydrolysis. Spectrophotometric (in aqueous solution at 212 or 270 nm) and spectrofluorometric (in 1N acetic acid, at 270/368 nm) methods of butobendin assay in tablets were elaborated and found to yield precise and reproducible results.
布托苯丁的电子光谱在pH值1.00至10.89之间稳定,但在pH值10.89至2.19范围内会因水解而随pH值变化。已详细阐述了片剂中布托苯丁的分光光度法(在212或270nm的水溶液中)和荧光分光光度法(在1N乙酸中,于270/368nm),并发现这些方法能产生精确且可重复的结果。