• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

甲状腺功能亢进症是否易导致硫利达嗪引起的高热和心律失常？

Does hyperthyroidism predispose to thioridazine-induced hyperpyrexia and cardiac arrhythmias?

作者信息

Murphy M B, FitzGerald M X

出版信息

Postgrad Med J. 1984 Jun;60(704):445-6. doi: 10.1136/pgmj.60.704.445.

DOI:10.1136/pgmj.60.704.445
PMID:6462991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2417892/
Abstract

Treatment with thioridazine resulted in hyperpyrexia and ventricular tachycardia in a young woman who was later shown to have thyrotoxicosis. The reasons why hyperthyroidism may enhance thioridazine toxicity are reviewed.

摘要

一名年轻女性在接受硫利达嗪治疗后出现高热和室性心动过速，后来被诊断为甲状腺毒症。本文综述了甲状腺功能亢进可能增强硫利达嗪毒性的原因。

相似文献

1
Does hyperthyroidism predispose to thioridazine-induced hyperpyrexia and cardiac arrhythmias?甲状腺功能亢进症是否易导致硫利达嗪引起的高热和心律失常？
Postgrad Med J. 1984 Jun;60(704):445-6. doi: 10.1136/pgmj.60.704.445.
2
Thioridazine-induced hyperpyrexia--a case report.硫利达嗪所致高热——病例报告
Am J Hosp Pharm. 1979 May;36(5):674-8.
3
Case report: successful treatment of ventricular tachycardia associated with thioridazine (Mellaril).病例报告：成功治疗与硫利达嗪（美立廉）相关的室性心动过速。
South Med J. 1969 Mar;62(3):357-8.
4
Recurrent major ventricular arrhythmias associated with thioridazine therapy.与硫利达嗪治疗相关的复发性严重室性心律失常。
Minn Med. 1971 Nov;54(11):877-80.
5
Ventricular arrhythmias associated with use of thioridazine hydrochloride in alcohol withdrawal.与盐酸硫利达嗪用于酒精戒断相关的室性心律失常。
Br Med J. 1973 Nov 24;4(5890):467. doi: 10.1136/bmj.4.5890.467.
6
Cardiac toxicity with thioridazine-tricyclic antidepressant combination.硫利达嗪与三环类抗抑郁药联用的心脏毒性
J Nerv Ment Dis. 1977 Aug;165(2):139-43. doi: 10.1097/00005053-197708000-00008.
7
Ventricular tachycardia associated with desipramine and thioridazine.与地昔帕明和硫利达嗪相关的室性心动过速。
Psychosomatics. 1990 Winter;31(1):100-3. doi: 10.1016/S0033-3182(90)72225-6.
8
Thioridazine-induced torsade de pointes. Successful therapy with isoproterenol.
JAMA. 1983 Jun 3;249(21):2931-4.
9
Iatrogenic torsade de pointes induced by thioridazine.硫利达嗪诱发的医源性尖端扭转型室性心动过速。
Biol Psychiatry. 1987 Jan;22(1):99-103. doi: 10.1016/0006-3223(87)90135-1.
10
Choreoathetosis associated with thioridazine: three case reports and literature review.与硫利达嗪相关的舞蹈手足徐动症：三例报告及文献综述。
Psychiatr Med. 1988;6(3):52-8.

本文引用的文献

1
HYPOTHERMIA FOLLOWING CHLORPROMAZINE THERAPY IN MYXOEDEMATOUS PATIENTS.
Gerontol Clin (Basel). 1964;6:252-6. doi: 10.1159/000244837.
2
Thyroxine-induced changes in characteristics and activities of beta-adrenergic receptors and adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate systems in the heart may be related to reputed catecholamine supersensitivity in hyperthyroidism.甲状腺素引起的心脏中β-肾上腺素能受体特性和活性以及3',5'-环磷酸腺苷和3',5'-环磷酸鸟苷系统的变化，可能与甲状腺功能亢进症中所谓的儿茶酚胺超敏反应有关。
Endocrinology. 1980 Jul;107(1):6-16. doi: 10.1210/endo-107-1-6.
3
The effect of thioridazine hydrochloride and chlorpromazine on the electrocardiogram.盐酸硫利达嗪和氯丙嗪对心电图的影响。
JAMA. 1966 Oct 3;198(1):134-8. doi: 10.1001/jama.198.1.134.
4
Death associated with ventricular arrhythmia and thioridazine hydrochloride.与室性心律失常及盐酸硫利达嗪相关的死亡
JAMA. 1968 Jul 8;205(2):108-10.
5
Temperature changes induced by chlorpromazine and N-methyl chlorpromazine in the rat.氯丙嗪和N-甲基氯丙嗪对大鼠体温的影响
Neuropharmacology. 1971 Jan;10(1):61-6. doi: 10.1016/0028-3908(71)90009-8.
6
Recurrent major ventricular arrhythmias associated with thioridazine therapy.与硫利达嗪治疗相关的复发性严重室性心律失常。
Minn Med. 1971 Nov;54(11):877-80.
7
Death attributed to ventricular arrhythmia induced by thioridazine in combination with a single Contac C capsule.死亡归因于硫利达嗪与一粒康泰克胶囊联用诱发的室性心律失常。
Can Med Assoc J. 1978 Oct 7;119(7):729-31.
8
Malignant hyperthermia. An allergic reaction to thioridazine therapy.恶性高热。对硫利达嗪治疗的过敏反应。
Arch Intern Med. 1978 May;138(5):800-1. doi: 10.1001/archinte.138.5.800.
9
Thioridazine-induced hyperpyrexia--a case report.硫利达嗪所致高热——病例报告
Am J Hosp Pharm. 1979 May;36(5):674-8.
10
Effects of thioridazine (Mellaril) on ventricular electrophysiologic properties.
Am J Cardiol. 1979 Jun;43(6):1155-8. doi: 10.1016/0002-9149(79)90147-4.