Smidt-Jensen S, Hahnemann N
Prenat Diagn. 1984 May-Jun;4(3):163-9. doi: 10.1002/pd.1970040302.
A technique for sampling first trimester chorionic villi for prenatal diagnosis by transabdominal fine needle biopsy is described. Specimens of chorionic villi were obtained from 49 out of 58 women, a success rate of 84.5 per cent. No fetal or maternal complications were demonstrated in the period before abortion. The procedure is useful for obtaining fetal tissue for culturing, DNA analysis and direct chromosome analysis.
本文描述了一种经腹细针穿刺活检获取孕早期绒毛进行产前诊断的技术。58名妇女中有49名成功获取了绒毛样本，成功率为84.5%。流产前未发现胎儿或母体并发症。该方法有助于获取胎儿组织进行培养、DNA分析和直接染色体分析。
