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[酒精摄入对大鼠体内矿物质组成的影响]

[Impact of alcohol consumption on the mineral composition of the body in the rat].

作者信息

Vaquero M P, Navarro M P, Conde R

出版信息

Rev Esp Fisiol. 1984 Mar;40(1):95-101.

PMID:6463346
Abstract

The influence of consumption of increasing ethanol solutions of 5, 7.5 and 10%/99.5% (v/v), on total body mineral composition, but particularly the ethanol effect on the contents of Ca, P, Mg, Zn, Na and K, for eight weeks was studied in the adult rat. Both females and males voluntarily lower their liquid intake when daily ethanol ingestion is about 1.4 and 1.7 g, respectively. These ethyl ingestions introduce some modifications in male body composition, but not in females, with an increase in the relative water content and a decrease of the carcass dry substance. The latter would be the main reason for the decrease in male body content of Ca, P, Zn, Mg and K, at least from the 7.5% v/v solution. Ca, P and Zn seem to be the most modified elements. Likewise, there are negative influences regarding Na, but they are not clearly evidenced until ethanol consumption reaches 1.9 g per day. Female body weight did not undergo any change, under any tested experimental conditions or their body ashes suffer any deterioration.

摘要

研究了成年大鼠连续八周摄入浓度递增的5%、7.5%和10%/99.5%(v/v)乙醇溶液对全身矿物质组成的影响,尤其是乙醇对钙、磷、镁、锌、钠和钾含量的影响。当每日乙醇摄入量分别约为1.4克和1.7克时,雌性和雄性大鼠都会自愿减少液体摄入量。这些乙醇摄入量会使雄性大鼠的身体组成发生一些变化,但对雌性大鼠没有影响,雄性大鼠的相对含水量增加,胴体干物质减少。至少从7.5%(v/v)的溶液开始,后者可能是雄性大鼠体内钙、磷、锌、镁和钾含量降低的主要原因。钙、磷和锌似乎是受影响最大的元素。同样,乙醇对钠也有负面影响,但直到乙醇摄入量达到每天1.9克时,这种影响才明显显现出来。在任何测试实验条件下,雌性大鼠的体重都没有变化,其骨灰也没有任何恶化。

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