Leroy M, Jaeger-Denavit O, Liot F
Rev Mal Respir. 1984;1(1):51-8.
Subjects with a complete paralysis of the abdominal muscles and severe or lesser involvement of the intercostals were studied. The author analysed, under electromyographic control, the flow-volume curves by measuring flow at 50% (V50) and at 25% (V25) of the observed and theoretical vital capacity (CV) above observed residual volume. The results were compared to a group of normal subjects in three situations: sitting and lying in air and sitting in water. A sloping, head down position was also studied. In the handicapped, instantaneous flow at 50% CV was significantly lower than normals in all situations; at 25% CV the difference was not significant but expiration was incomplete for those sitting in air. For the handicapped, sitting in water, the residual volume was close to that of normal subjects sitting in air and the last part of the flow-volume curve was the same gradient as of normal subjects sitting in air: this enabled some comparisons of instantaneous flow. In order that measures of instantaneous flow were made at the same inflation volume, they were made at 50% and 25% of theoretical vital capacity in the handicapped. The results did not differ from those of normal subjects sitting in air. The situation was less satisfactory lying in air, only useable in practice, the most handicapped subjects having notably reduced outputs compared to those whose motor deficit was less severe. The head down position was as for outputs at very low volume.
对腹肌完全麻痹且肋间肌有严重或较轻受累的受试者进行了研究。作者在肌电图控制下，通过测量高于实测残气量的实测和理论肺活量（CV）的50%（V50）和25%（V25）时的流量，分析流量-容积曲线。将结果与一组正常受试者在三种情况下进行比较：在空气中坐立和躺卧以及在水中坐立。还研究了头部向下倾斜的姿势。在残疾受试者中，在所有情况下，CV为50%时的瞬时流量均显著低于正常人；CV为25%时，差异不显著，但对于在空气中坐立的受试者，呼气不完全。对于在水中坐立的残疾受试者，残气量接近在空气中坐立的正常受试者，且流量-容积曲线的最后部分与在空气中坐立的正常受试者具有相同的斜率：这使得能够对瞬时流量进行一些比较。为了在相同的充气量下测量瞬时流量，在残疾受试者中，在理论肺活量的50%和25%时进行测量。结果与在空气中坐立的正常受试者的结果没有差异。在空气中躺卧的情况不太理想，在实际应用中仅在部分情况下可用，与运动功能缺损较轻的受试者相比，残疾最严重的受试者的输出量明显降低。头部向下倾斜的姿势对于极低流量时的输出量情况也是如此。
