Graveleau P, Henin D, Masson M, Daumas-Duport C, Graveleau J, Cambier J
Rev Neurol (Paris). 1984;140(5):330-42.
Clinical and pathological findings in three adults with toxoplasmosis of the central nervous system are reported. Symptoms and signs in the first patient, a Haitian woman who had lived in France for 2 years, were suggestive of a right hemispheric space-occupying process. The second case was a woman treated for Hodgkin's disease who showed symptoms and signs of a meningoencephalitis. The presenting lesion in case 3 mimicked a tumor of the posterior fossa. Analysis of these 3 cases and of those previously reported underlines: 1) diagnostic difficulties, particularly in immunodepressed patients; 2) the effectiveness of immunoperoxidase for pathological diagnosis; 3) the poor prognosis due to absence of a specific treatment.
报告了3例成人中枢神经系统弓形虫病的临床和病理表现。首例患者为一名在法国生活了2年的海地女性,其症状和体征提示右半球占位性病变。第二例是一名接受过霍奇金病治疗的女性,表现出脑膜脑炎的症状和体征。第3例患者最初的病变类似后颅窝肿瘤。对这3例病例以及先前报道的病例进行分析后强调:1)诊断困难,尤其是在免疫抑制患者中;2)免疫过氧化物酶在病理诊断中的有效性;3)由于缺乏特异性治疗,预后较差。