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[1例与抗-Wra(赖特)抗体相关的新生儿溶血病]

[A case of hemolytic disease in a newborn associated with anti-Wra (WRIGHT) antibodies].

作者信息

Monestier M, Juron-Dupraz F, Meyer F, Rigal D

出版信息

Rev Fr Transfus Immunohematol. 1984 Apr;27(2):271-5. doi: 10.1016/s0338-4535(84)80041-0.

DOI:10.1016/s0338-4535(84)80041-0
PMID:6463512
Abstract

A french woman delivered a third full-term male baby who had a strongly positive direct antiglobulin test. During the pregnancy and after the delivery, the woman had a negative irregular antibody screening test using standard red blood cell panels. The compatibility testing between the mother's serum and the father's red blood cells was strongly positive and the antibody was identified as an anti-Wra. The baby developed a mild hyperbilirubinemia and recovered without treatment. This child was probably responsible for his mother's immunization since the two previous children were Wra negative and the mother had no history of blood transfusion or abortion.

摘要

一名法国女性分娩了第三个足月男婴,该男婴的直接抗球蛋白试验呈强阳性。在孕期及分娩后,该女性使用标准红细胞检测板进行的不规则抗体筛查试验结果为阴性。母亲血清与父亲红细胞之间的交叉配血试验呈强阳性,抗体被鉴定为抗-Wra。婴儿出现轻度高胆红素血症,未经治疗即康复。由于前两个孩子为Wra阴性,且母亲无输血或流产史,这个孩子可能是导致母亲产生免疫反应的原因。

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