Rigal D, Juron-Dupraz F, Biggio B, Jouvenceaux A
Rev Fr Transfus Immunohematol. 1982 Feb;25(1):101-4. doi: 10.1016/s0338-4535(82)80083-4.
The first case is provided by a french women (KK, husband k/k) who delivered a first healthy full term infant in 1970 and received one blood unit at this time. In 1972 and 1975, his second and fourth pregnancies ended by spontaneous abortion. In 1974 and 1976, she delivered stillborn infants with hydrops fetalis during the sixth month. In serum, anti-k antibody reacted by the indirect antiglobulin test with a titer of 4 096. In the second case, french women delivered a first full term female infant who had a strongly positive direct antiglobulin test. The mother had received one blood unit ten years before during nephrectomy. Her red blood cell were KK and her husband was kk. She had a anti-Cellano in serum reactive in the indirect antiglobulin test with a titer of 16. The infant developed a mild hyperbilirubinemia and recovered without treatment these two cases confirm the variable effect of maternal anti-k antibody evidenced by few other published cases.
第一个病例是一位法国女性(KK,丈夫为k/k),她于1970年产下第一个健康的足月婴儿,当时接受了一个单位的血液。1972年和1975年,她的第二次和第四次怀孕以自然流产告终。1974年和1976年,她在第六个月时产下患有胎儿水肿的死产婴儿。血清中,抗-k抗体通过间接抗球蛋白试验反应,滴度为4096。在第二个病例中,一位法国女性产下第一个足月女婴,该女婴直接抗球蛋白试验呈强阳性。母亲在十年前肾切除术中接受了一个单位的血液。她的红细胞为KK型,丈夫为kk型。她血清中有抗塞拉诺抗体,通过间接抗球蛋白试验反应,滴度为16。婴儿出现轻度高胆红素血症,未经治疗即康复。这两个病例证实了母体抗-k抗体的可变效应,其他一些已发表的病例也证明了这一点。