Tendera M, Campbell W B, Moyers J R
South Med J. 1984 Aug;77(8):990-4. doi: 10.1097/00007611-198408000-00014.
In a community hospital, we correlated results of thallium 201 myocardial scintigraphy with coronary arteriographic data in 79 patients. Scintigraphy was 92% sensitive and 85% specific in detecting coronary artery disease. There were no false-negative scintigrams in patients with double or triple vessel disease. The most important factors determining sensitivity of the method in detecting individual coronary stenoses were (1) location of the stenosis in the coronary tree, (2) number of vessels involved, and (3) degree of obstruction. Higher prevalence of perfusion defects in areas of 90% to 99% stenosis as compared with 50% to 89% lesions was of borderline statistical significance (86% vs 59%; P = .06). Myocardial perfusion scintigraphy was unable to predict the number of significantly narrowed coronary vessels. Predictive value of a perfusion defect for a significant coronary stenosis was 87% for anterior, 88% for septal, 90% for lateral, 89% for posterior, and 78% for inferior segment. We conclude that segmental analysis of myocardial scintigrams may be of value in a community hospital.
在一家社区医院,我们将79例患者的201铊心肌闪烁扫描结果与冠状动脉造影数据进行了对比。在检测冠状动脉疾病方面,闪烁扫描的敏感性为92%,特异性为85%。双支或三支血管病变患者中没有出现假阴性闪烁扫描结果。决定该方法检测单个冠状动脉狭窄敏感性的最重要因素为:(1)冠状动脉树中狭窄的位置;(2)受累血管的数量;(3)阻塞程度。与50%至89%狭窄病变相比,90%至99%狭窄区域灌注缺损的发生率更高,具有临界统计学意义(86%对59%;P = 0.06)。心肌灌注闪烁扫描无法预测严重狭窄的冠状动脉血管数量。灌注缺损对严重冠状动脉狭窄的预测价值在前壁为87%,在间隔为88%,在侧壁为90%,在后壁为89%,在下壁为78%。我们得出结论,在社区医院中,心肌闪烁扫描的节段性分析可能具有价值。