肾病综合征中的血浆可溶性纤维蛋白单体复合物——关于低白蛋白血症

Plasma soluble fibrin monomer complexes in nephrotic syndrome--with reference to hypoalbuminemia.

作者信息

Iioka Y, Kikuchi K, Tada H, Isogai S, Urayama T

出版信息

Tohoku J Exp Med. 1984 May;143(1):53-7. doi: 10.1620/tjem.143.53.

DOI:10.1620/tjem.143.53

Abstract

Plasma soluble fibrin monomer complexes (SFMC) in 10 patients with nephrotic syndrome were measured to demonstrate the contribution of hypoalbuminemia to the SFMC formation. The levels of SFMC as well as plasma fibrinogen (Fbg) levels were significantly higher than those in control subjects. There was a negative correlation between the levels of SFMC and serum albumin, and also between Fbg and serum albumin. The increase in SFMC levels which indicates the intravascular generation of thrombin might be correlated to hypoalbuminemia in nephrotic syndrome with hypercoagulability.

摘要

检测了10例肾病综合征患者的血浆可溶性纤维蛋白单体复合物（SFMC），以证明低白蛋白血症对SFMC形成的影响。SFMC水平以及血浆纤维蛋白原（Fbg）水平显著高于对照组。SFMC水平与血清白蛋白之间以及Fbg与血清白蛋白之间均呈负相关。提示血管内凝血酶生成的SFMC水平升高可能与肾病综合征伴高凝状态下的低白蛋白血症相关。