Isogai S, Kikuchi K, Kameyama M, Oshima Y, Urayama T, Komoto M
Tohoku J Exp Med. 1982 Aug;137(4):409-13. doi: 10.1620/tjem.137.409.
To elucidate the relationship between plasma soluble fibrin monomer complexes (SFMC) and retinal or vitreous hemorrhages, 11 diabetics were studied for 15 months. The levels of SFMC in 3 out of the 11 cases were elevated prior to hemorrhages and in the other 8 cases SFMC levels were elevated after hemorrhages. With regard to fibrinogen (Fbg) concentrations, there was no significant difference between the values before and after hemorrhages. The plasma glucose levels did not change significantly during the observation. It was concluded that the SFMC level was not only an indicator of the intracapillary generation of thrombin but an important factor affecting the development of diabetic retinopathy.
为了阐明血浆可溶性纤维蛋白单体复合物（SFMC）与视网膜或玻璃体出血之间的关系，对11名糖尿病患者进行了15个月的研究。11例患者中有3例在出血前SFMC水平升高，另外8例在出血后SFMC水平升高。关于纤维蛋白原（Fbg）浓度，出血前后的值没有显著差异。观察期间血糖水平没有明显变化。得出的结论是，SFMC水平不仅是毛细血管内凝血酶生成的指标，也是影响糖尿病视网膜病变发展的重要因素。
