Ruiz-Maldonado R, Tamayo L, Fernández-Diez J
Arch Dermatol. 1978 May;114(5):775-8.
A Mexican child was born white and progressively became black. At the age of 21 months, the whole integument was deep black in the absence of other alterations. Electron microscopy showed a Negroid pattern in the epidermal melanosomes. Among the different forms of progressive mucocutaneous pigmentations previously described in the literature, we were unable to find a similar case.
一名墨西哥儿童出生时皮肤白皙,后来逐渐变黑。在21个月大时,全身皮肤呈现深黑色,未出现其他异常。电子显微镜检查显示表皮黑素小体呈现黑人样模式。在文献中先前描述的各种进行性黏膜皮肤色素沉着形式中,我们未能找到类似病例。