Department of Pediatrics, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
Indian J Pediatr. 2012 Aug;79(8):1094-6. doi: 10.1007/s12098-011-0576-9.
Generalized pigmentation in a child may be seen in a variety of disorders which can be clinically differentiated. Accuracy of diagnosis can be increased by classifications based on both clinical and histological findings. The authors report a case of siblings in whom hyperpigmentation started at age of about 6 mo and was progressing. Histology of skin revealed shortening and blunting of rete ridges with presence of melanocytes in stratum basal layer. This is a rare type of hypermelanosis and termed as universal acquired melanosis or carbon baby syndrome. This is a rare presentation and first case report in siblings.
儿童的全身性色素沉着可见于多种可临床区分的疾病。基于临床和组织学发现的分类可提高诊断的准确性。作者报告了一对兄弟姐妹的病例，他们的色素沉着从大约 6 个月大开始，并逐渐加重。皮肤组织学显示，网嵴缩短变钝，基底层有黑素细胞存在。这是一种罕见的黑素增多症，称为全身性获得性黑素沉着症或碳宝宝综合征。这是一种罕见的表现形式，也是首例在兄弟姐妹中报道的病例。
