重型β地中海贫血中循环免疫复合物的出现
Occurrence of circulating immune complexes in beta-thalassaemia major.
作者信息
Casali P, Borzini P, Vergani D, Mieli-Vergani G, Masera G, Zanussi C
出版信息
Arch Dis Child. 1978 Feb;53(2):141-3. doi: 10.1136/adc.53.2.141.
The presence of circulating soluble immune complexes and the level of complement were investigated in sera from 21 patients with beta-thalassaemia major, including both splenectomised and nonsplenectomised patients. A high level of immune complexes was found in half of these cases. Reduced complement levels were seen less frequently. There was no correlation between the presence of circulating immune complexes, decreased complement levels, and thpresence or absence of the spleen. The level of immune complexes increased with the age ofthe individual, i.e. with the duration of the disease.
对21例重型β地中海贫血患者（包括脾切除患者和未脾切除患者）的血清进行了循环可溶性免疫复合物及补体水平的研究。在其中半数病例中发现了高水平的免疫复合物。补体水平降低的情况较少见。循环免疫复合物的存在、补体水平降低与脾脏的有无之间没有相关性。免疫复合物水平随个体年龄增加，即随疾病持续时间增加而升高。
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