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子宫内膜癌的长期生存,特别提及年龄作为一个预后因素。

Long-term survival in endometrial cancer with special reference to age as a prognostic factor.

作者信息

Persson I, Adami H O, Malker B, Pettersson B

出版信息

Ups J Med Sci. 1984;89(2):159-70. doi: 10.3109/03009738409178476.

Abstract

Long-term survival was evaluated in 13 586 patients with cancer of the endometrium, constituting 97% of all cases diagnosed in Sweden 1960-1978. Survival rates corrected for the expected mortality revealed that age at diagnosis is an important predictor of prognosis, with a constant trend towards a more favourable course in younger women. Thus, the cumulative relative 15-year survival rates +/- 95% confidence limits were 90 (86.1-93.7)%, 89 (87.4-91.3)%, 72 (68.9-74.3)%, 50 (44.9-54.7)% and 32 (18.3-45.6)% at ages 35-44, 45-54, 55-64, 65-74 and 75+ years respectively. Patients younger than 55 years deviated from the general pattern by having an excellent survival and virtually no excess mortality after 7 years of observation.

摘要

对13586例子宫内膜癌患者的长期生存率进行了评估,这些患者占1960年至1978年瑞典确诊的所有病例的97%。经预期死亡率校正后的生存率显示,确诊时的年龄是预后的重要预测指标,年轻女性的病情发展趋势始终更为有利。因此,35至44岁、45至54岁、55至64岁、65至74岁和75岁及以上年龄组的累积相对15年生存率±95%置信区间分别为90(86.1 - 93.7)%、89(87.4 - 91.3)%、72(68.9 - 74.3)%、50(44.9 - 54.7)%和32(18.3 - 45.6)%。55岁以下的患者与总体模式不同,其生存率极佳,观察7年后几乎没有额外死亡率。

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