Visconti E B, Peters R W, Cangir A, Zorn G L, Fisher S
Arch Dis Child. 1978 Apr;53(4):342-4. doi: 10.1136/adc.53.4.342.
Adrenal cortical carcinoma in a 4 1/4-month-old girl was treated by surgery in combination with actinomycin D, cyclophosphamide, and 5-fluorouracil given daily for 5 days every third week for 13 1/2 months. Postoperative hypertension and raised 24-hour 17-hydroxy- and 21-oxosteroids suggested residual microscopical tumour activity. These findings resolved during chemotherapy. The patient is alive and well 22 months after completing chemotherapy. Adrenal cortical carcinoma may rarely mimic neuroblastoma or nephroblastoma when the tumour is not clinically secretory.
一名4个半月大的女孩患肾上腺皮质癌,接受了手术治疗,并联合使用放线菌素D、环磷酰胺和5-氟尿嘧啶,每三周连续5天每日给药,共治疗13个半月。术后高血压以及24小时尿17-羟类固醇和21-氧类固醇升高提示存在显微镜下残留的肿瘤活性。这些表现在化疗期间消失。完成化疗22个月后,患者健在。当肾上腺皮质癌无临床分泌表现时,可能很少会酷似神经母细胞瘤或肾母细胞瘤。