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[小肠不同节段切除术后胃酸分泌的变化。大鼠实验研究]

[Changes in the secretion of gastric acid following resection of different segments of the small intestine. An experimental study on rats].

作者信息

Fleck U, Nowak W, Blech W

出版信息

Z Exp Chir Transplant Kunstliche Organe. 1984;17(3):168-78.

PMID:6464525
Abstract

Gastric acid secretion after small bowel resection was studied on 46 Wistar-rats using a perfusion method like gastrin-bioassay of Lai. Basal acid output (BAO) and peak acid output (PAO) was increased in 2 of 7 rats with proximal small bowel resection (75%). Peak acid output was significantly decreased after distal small bowel resection (66%). The results suggest that gastric hypersecretion is not a regular effect of subtotal intestinal resection. We concluded there is no fear of a regular peptic ulcer disease after massive small bowel resection.

摘要

采用类似赖氏胃泌素生物测定法的灌注方法,对46只Wistar大鼠进行小肠切除术后胃酸分泌的研究。7只近端小肠切除的大鼠中有2只(75%)基础酸排出量(BAO)和最大酸排出量(PAO)增加。远端小肠切除术后最大酸排出量显著降低(66%)。结果表明,胃酸分泌过多并非小肠部分切除的常规效应。我们得出结论,大面积小肠切除术后无需担心会经常发生消化性溃疡疾病。

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1
[Changes in the secretion of gastric acid following resection of different segments of the small intestine. An experimental study on rats].[小肠不同节段切除术后胃酸分泌的变化。大鼠实验研究]
Z Exp Chir Transplant Kunstliche Organe. 1984;17(3):168-78.
2
Increased gastric acid secretion after massive small bowel resection is related to a decrease in enterogastrones.大量小肠切除术后胃酸分泌增加与肠抑胃素减少有关。
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