培养中的类风湿性滑膜细胞产生一种生长抑制剂。
Rheumatoid synovial cells in culture produce a growth inhibitor.
作者信息
Smith C A
出版信息
Ann Rheum Dis. 1978 Apr;37(2):187-9. doi: 10.1136/ard.37.2.187.
Abstract
Cultures of synovial cells obtained at surgery from patients with rheumatoid arthritis produced a protein which inhibits the mitosis of normal rabbit and human synovial cells, and of human lung fibroblasts. This mitotic inhibitory effect can be transferred to rabbit synovial cells by intra-articular injection of the animals with rheumatoid synovial cell cultures.
摘要
从类风湿性关节炎患者手术中获取的滑膜细胞培养物产生了一种蛋白质，该蛋白质可抑制正常兔和人滑膜细胞以及人肺成纤维细胞的有丝分裂。通过向兔关节腔内注射类风湿性滑膜细胞培养物，这种有丝分裂抑制作用可转移至兔滑膜细胞。
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