Kitazawa M, Kaneko H, Toshima M, Ishikawa H, Kobayashi H, Sekiya M
Acta Pathol Jpn. 1984 May;34(3):687-92. doi: 10.1111/j.1440-1827.1984.tb07597.x.
An autopsy case of a 45 years old Japanese female with malignant masothelioma showing peculiar stromal change was presented. The tumor had occupied the abdominal cavity around the uterus and both ovaries, and was diagnosed as a malignant peritoneal mesothelioma of epithelial type. The characteristic feature of the tumor was that the foam cells, which contained abundant amount of lipid droplets in the cytoplasm, and were thought to be histiocytes, massively occupied the stroma of the papillary tumor. Macroscopically, the tumor simulated a codfish roe. To our knowledge, no case of this sort of appearance of mesothelioma has ever been reported.
报告了一例45岁日本女性恶性间皮瘤的尸检病例,该肿瘤呈现出特殊的间质变化。肿瘤占据了子宫及双侧卵巢周围的腹腔,被诊断为上皮型恶性腹膜间皮瘤。该肿瘤的特征是,泡沫细胞大量占据乳头状肿瘤的间质,这些泡沫细胞胞质内含有大量脂滴,被认为是组织细胞。大体上,肿瘤类似鳕鱼卵。据我们所知,此前从未有过这种外观的间皮瘤病例报道。