Svindland A
Acta Pathol Microbiol Immunol Scand A. 1984 May;92(3):177-83. doi: 10.1111/j.1699-0463.1984.tb04393.x.
The localization of macroscopic atherosclerotic lesions have been studied in the basilar bifurcation and the left and right internal carotid bifurcations in humans. The distribution of lesions was separately assessed by a computer technique and results were displayed as contour lines. Lesions are most frequent on the outer walls of the bifurcations and on the inner curvature of the arterial bends. The material was processed for histology, and computerised morphometry was used to study the interrelationship of microscopic atheromatous lesions and intimal thickening. The percentage of the specimens with lesions around the circumference of the arteries was calculated. The peaks and troughs The peaks and troughs of histological lesions correspond exactly to the maximum and minimum contours of the macroscopic studies. Results from the microscopic examination indicate that intimal thickening and atherosclerosis are closely related processes. However, they cannot support the view that focal pad-like areas of intimal thickening are particular precursors of atheroma.
对人类基底动脉分叉处以及左右颈内动脉分叉处的宏观动脉粥样硬化病变定位进行了研究。通过计算机技术分别评估病变分布，并将结果显示为等高线。病变最常出现在分叉处的外壁以及动脉弯曲的内曲率处。对材料进行了组织学处理，并使用计算机形态计量学研究微观动脉粥样硬化病变与内膜增厚之间的相互关系。计算了动脉周围有病变的标本的百分比。组织学病变的波峰和波谷与宏观研究的最大和最小轮廓完全对应。显微镜检查结果表明，内膜增厚与动脉粥样硬化是密切相关的过程。然而，它们无法支持内膜增厚的局灶性垫状区域是动脉粥样硬化特定先兆的观点。
