Jones R C
Ann Surg. 1978 May;187(5):555-64. doi: 10.1097/00000658-197805000-00015.
Since 1950, 300 patients sustaining pancreatic injuries have been managed. Three-fourths of the injuries were due to penetrating trauma with a 20% mortality and one-fourth due to blunt trauma resulting in an 18% mortality. The pancreatic injury was responsible for death in only 3% of patients. Early onset of shock resulted in 38% mortality whereas only 4% of normotensive patients died. No patient died of an isolated pancreatic injury. Sepsis was the second most common cause of death following hemorrhage. Preoperative serum amylase was elevated more frequently following blunt trauma than penetrating trauma, but did not correlate with injury. There has been a tendency toward more frequent use of distal pancreatectomy for simple penetrating injuries without obvious ductal violation which increases operative time, blood loss and possible intra-abdominal abscess since resection usually requires splenectomy. Patients considered for an 80% distal resection are better managed with a Roux-en-Y limb to the distal pancreas since three patients developed diabetes following an 80% or greater resection. A conservative approach consisting of Penrose and sump drainage is adequate for most injuries.
自1950年以来,共处理了300例胰腺损伤患者。四分之三的损伤由穿透性创伤所致,死亡率为20%;四分之一由钝性创伤所致,死亡率为18%。胰腺损伤仅导致3%的患者死亡。早期休克导致38%的患者死亡,而血压正常的患者仅有4%死亡。没有患者死于单纯的胰腺损伤。脓毒症是继出血之后的第二大常见死亡原因。钝性创伤后术前血清淀粉酶升高比穿透性创伤更常见,但与损伤无关。对于无明显导管损伤的单纯穿透性损伤,远端胰腺切除术的使用频率有增加的趋势,这会增加手术时间、失血量及可能发生的腹腔内脓肿,因为切除通常需要行脾切除术。对于考虑行80%远端切除术的患者,采用Roux-en-Y袢与远端胰腺吻合的方式处理更好,因为80%或更大范围切除术后有3例患者发生了糖尿病。对于大多数损伤,采用彭罗斯引流管和烟卷引流的保守方法就足够了。