Hills B A, Cotton D B
Am J Obstet Gynecol. 1984 Aug 15;149(8):896-902. doi: 10.1016/0002-9378(84)90612-4.
Thirty-one human placental membranes of various gestational ages (24 1/2 to 42 weeks) have been studied for their surface properties by use of a goniometer to observe drops of saline and olive oil applied at regular intervals to the amniotic and chorionic surfaces as they dried in air. Results show that the epithelial surfaces of the chorion and amnion and their interface are all appreciably hydrophobic. Surface energy decreased on the amniotic surface with fetal maturity while the surface energy of the chorion was significantly (137%) higher in those displaying premature rupture of the membranes than in others of comparable gestational age. This is explained on the basis that low-energy surfaces (for instance, Teflon) do not stick and provide boundary lubrication which facilitates movement. These properties are needed to avoid the buildup of local mechanical stress which could initiate rupture. It is speculated that the release agent-lubricant is surfactant derived from amniotic fluid and directly adsorbed onto the epithelial walls. On other tissues, the same surfactants have been shown to reduce surface energy, rendering them hydrophobic and imparting many desirable properties such as release, lubrication, and resistance to erosion.
通过使用测角仪，观察不同胎龄（24.5至42周）的31个人类胎盘膜在空气中干燥时，定期滴加在羊膜和绒毛膜表面的盐水和橄榄油滴的情况，以此研究其表面特性。结果表明，绒毛膜和羊膜的上皮表面及其界面均明显具有疏水性。随着胎儿成熟，羊膜表面的表面能降低，而在胎膜早破的胎盘膜中，绒毛膜的表面能比相同胎龄的其他胎盘膜显著高出137%。这可以基于低能表面（例如特氟龙）不粘连并提供边界润滑从而促进运动来解释。这些特性对于避免可能引发破裂的局部机械应力积累是必需的。据推测，脱模剂-润滑剂是源自羊水并直接吸附在上皮壁上的表面活性剂。在其他组织上，相同的表面活性剂已被证明可降低表面能，使其具有疏水性，并赋予许多理想特性，如脱模、润滑和抗侵蚀性。
