Hills B A
Paediatric Respiratory Research Centre, Mater Children's Hospital, South Brisbane, Queensland.
Aust N Z J Obstet Gynaecol. 1995 May;35(2):186-9. doi: 10.1111/j.1479-828x.1995.tb01866.x.
Surface-active phospholipid (SAPL) extracted from amniotic fluid or elutriated from the chorioamnionic sacs of placentas recovered from normal full term deliveries has been shown to be a remarkable lubricant. Coefficients of kinetic and static friction were reduced to 0.009 by SAPL from amniotic fluid and 0.011 for a membrane extract, even under high load (3 kg/cm2), compared with 0.04 for the best nonbiological boundary lubricants. The antiwear properties were equally remarkable, giving a mean scar diameter under extreme pressure of only 0.76 mm for amniotic SAPL and 1.00 mm for membrane extract compared with 0.85-0.95 mm for aqueous lubricants commercially available. These results support the hypothesis that premature rupture (PROM) is less likely to occur if movement between the fetus and the amnion or between the decidual surface of the uterus and the chorion is well lubricated.
从正常足月分娩后回收的羊水中提取或从胎盘的绒毛羊膜囊中淘析得到的表面活性磷脂（SAPL）已被证明是一种出色的润滑剂。即使在高负荷（3千克/平方厘米）下，羊水来源的SAPL可将动摩擦系数和静摩擦系数降低至0.009，膜提取物的摩擦系数为0.011，而最佳非生物边界润滑剂的摩擦系数为0.04。其抗磨性能同样显著，在极压条件下，羊水SAPL的平均疤痕直径仅为0.76毫米，膜提取物为1.00毫米，相比之下，市售水性润滑剂的平均疤痕直径为0.85 - 0.95毫米。这些结果支持了这样一种假设，即如果胎儿与羊膜之间或子宫蜕膜表面与绒毛膜之间的运动得到良好润滑，那么胎膜早破（PROM）发生的可能性较小。
