Faraci F M, Kilgore D L, Fedde M R
Am J Physiol. 1984 Aug;247(2 Pt 2):R402-3. doi: 10.1152/ajpregu.1984.247.2.R402.
We determined the pulmonary pressor response during hypoxia in bar-headed geese (Anser indicus), a species that flies at altitudes up to 9,000 m, and Pekin ducks (Anas platyrhynchos), a non-flyer. Mean pulmonary arterial blood pressure (PAP) and arterial O2 partial pressure (PaO2) were measured in unanesthetized birds acutely exposed to 21, 10, 5, and, in geese only, 4% O2. PAP in geese did not change as PaO2 was reduced from 95 to 46 Torr and rose only 3 mmHg when PaO2 was reduced to 28 Torr. The same PaO2 decline in ducks (99 to 29 Torr) resulted in an 11-mmHg rise in PAP. The data suggest that very little or no increase in pulmonary vascular resistance occurs in these geese during hypoxia. This bird may provide a unique model in which to study pulmonary vascular control mechanisms.
我们测定了斑头雁（Anser indicus，一种能在高达9000米高空飞行的物种）和北京鸭（Anas platyrhynchos，一种不会飞行的物种）在低氧状态下的肺升压反应。在急性暴露于21%、10%、5%氧气环境以及仅对斑头雁暴露于4%氧气环境的未麻醉鸟类中，测量了平均肺动脉血压（PAP）和动脉血氧分压（PaO2）。当斑头雁的PaO2从95 Torr降至46 Torr时，PAP没有变化，而当PaO2降至28 Torr时，PAP仅升高了3 mmHg。北京鸭中相同的PaO2下降（从99 Torr降至29 Torr）导致PAP升高了11 mmHg。数据表明，这些斑头雁在低氧状态下肺血管阻力极少增加或没有增加。这种鸟类可能提供了一个研究肺血管控制机制的独特模型。
