一种新的、纯化的粉尘螨过敏原制剂。采用皮肤点刺试验（SPT）和放射变应原吸附试验（RAST）技术进行评估。

A new, purified Dermatophagoides farinae allergen preparation. Evaluation with SPT and RAST techniques.

作者信息

Moxnes A, Dale S, Andrew E, Halvorsen R

出版信息

Allergy. 1984 Jul;39(5):339-49. doi: 10.1111/j.1398-9995.1984.tb01951.x.

DOI:10.1111/j.1398-9995.1984.tb01951.x

Abstract

A purified, standardized and characterized allergen preparation of the house dust mite Dermatophagoides farinae (Df) was evaluated by skin prick test (SPT) and radioallergosorbent test (RAST) in 88 subjects. Skin reactions to the purified Df preparation and a corresponding crude Df preparation were compared. SPT was also performed with a crude Dermatophagoides pteronyssinus (Dpt) preparation to compare reactions obtained with the two mite preparations. By SPT the purified Df allergen preparation was representative of the crude Df preparation (r = 0.78) and the correlation between skin reactions to Df and Dpt was high (r = 0.78). The concordance between results obtained with RAST and SPT techniques with the purified Df preparation was high (84%). The purified D. farinae preparation was well tolerated and is well suited for SPT.

摘要

通过皮肤点刺试验（SPT）和放射变应原吸附试验（RAST）对88名受试者进行了纯化、标准化和特征明确的粉尘螨（Df）变应原制剂评估。比较了皮肤对纯化Df制剂和相应粗制Df制剂的反应。还用粗制的户尘螨（Dpt）制剂进行了SPT，以比较两种螨制剂的反应。通过SPT，纯化的Df变应原制剂代表了粗制Df制剂（r = 0.78），并且皮肤对Df和Dpt反应之间的相关性很高（r = 0.78）。RAST和SPT技术对纯化Df制剂的检测结果一致性很高（84%）。纯化的粉尘螨制剂耐受性良好，非常适合用于SPT。