Douchez J, Daly N, Combes P F, Lacomme Y
Ann Otolaryngol Chir Cervicofac. 1984;101(3):195-8.
Most of the carcinoma of the nasopharynx diagnosed in our country, are loco-regionally advanced disease. Thus 31/54 (57%) of our patients referred to the Centre Claudius Regaud between 1970 and 1980 were T2 N3, T3 N3, T4 N0 or N1 N2 N3. In spite of this poor initial presentation external radiotherapy can achieve a quite good rate of tumoral control inside the treated volume. In our series there were 17/47 (36%) tumoral and/or nodal recurrences and 7/47 (15%) metastases without local or regional failure. Improvement of initial évaluation of the tumoral volume is now obtained by the systematic use of C.A.T. and this procedure should reduce local failure rate. In the other hand, the association of chemotherapy and radiotherapy should be useful in treating advanced disease or poorly differentiated carcinomas with high metastatic risk.
在我国诊断出的大多数鼻咽癌都是局部区域晚期疾病。因此，1970年至1980年间转诊至克劳迪乌斯·雷高德中心的患者中，有31/54（57%）为T2 N3、T3 N3、T4 N0或N1 N2 N3。尽管初始表现不佳，但外照射放疗在治疗区域内仍可实现相当高的肿瘤控制率。在我们的系列研究中，有17/47（36%）出现肿瘤和/或淋巴结复发，7/47（15%）出现转移但无局部或区域失败。目前，通过系统使用计算机断层扫描（CAT）可改善对肿瘤体积的初始评估，这一程序应能降低局部失败率。另一方面，化疗与放疗联合应用对于治疗晚期疾病或具有高转移风险的低分化癌应是有用的。
