Wolfe J, Erickson R P, Rigby P W, Goodfellow P N
Ann Hum Genet. 1984 Jul;48(3):253-9. doi: 10.1111/j.1469-1809.1984.tb01022.x.
The structure of the Y chromosome and the relationship between the human sex chromosomes have been studied using Y-derived sequences cloned in cosmids. Two probes recognize different unique sequences which map to the heterochromatic part of the long arm of the Y chromosome. A third sequence is shared by the long arm of the X chromosome and the euchromatic part of the Y chromosome. Thus homology between the sex chromosomes occurs outside the pairing region.
利用克隆于黏粒中的Y衍生序列,对Y染色体的结构以及人类性染色体之间的关系进行了研究。两种探针识别不同的独特序列,这些序列定位于Y染色体长臂的异染色质部分。第三种序列为X染色体长臂和Y染色体常染色质部分所共有。因此,性染色体之间的同源性出现在配对区域之外。