Suppr超能文献

[3个月龄前接受主动脉缩窄手术的婴儿的结局]

[Outcome of infants operated on for aortic coarctation before 3 months of age].

作者信息

Tillous-Borde I, Losay J, Petit J, Lucet P, Binet J P, Planche C, Langlois J

出版信息

Arch Fr Pediatr. 1984 May;41(5):323-8.

PMID:6466031
Abstract

Between January 1966 and June 1982, 177 infants less than 3 months of age underwent surgical cure of coarctation of the aorta. Seventy-one percent had associated cardiac lesions not including a patent ductus arteriosus. With the cure of the coarctation either by resection anastomosis or angioplasty, 45% underwent associated surgical procedure, mainly pulmonary artery banding. Early mortality was 26% for the last 4 years of the study. Early deaths, significantly correlated with the severity of the preoperative heart failure and the importance of pulmonary hypertension, were not correlated with an associated heart disease. Of the 95 survivors operated on before December 31, 1981 and with a long follow-up, 18 died later on. Late deaths are related with associated cardiac malformations. Thirty-nine (41%) of the survivors had recurrent coarctation. This was correlated with the year of surgery and not with the surgical technique. In cases with coarctation of the aorta surgical cure should not be withheld before age 3 months, when there is heart failure, with or without associated cardiac malformations. The mortality, even in isolated coarctation (6%), the occurrence of sudden deaths after good surgical repair, the frequency of recoarctations lead to suggest that in infants under 3 months of age, careful supervision and conservative medical treatment should be considered, if the coarctation is isolated and well tolerated.

摘要

1966年1月至1982年6月期间,177名3个月以下的婴儿接受了主动脉缩窄的手术治疗。71%的患儿伴有心脏病变,但不包括动脉导管未闭。通过切除吻合术或血管成形术治愈缩窄后,45%的患儿接受了相关手术,主要是肺动脉环扎术。该研究最后4年的早期死亡率为26%。早期死亡与术前心力衰竭的严重程度和肺动脉高压的严重程度显著相关,与相关心脏病无关。在1981年12月31日前接受手术且随访时间长的95名幸存者中,有18人后来死亡。晚期死亡与相关心脏畸形有关。39名(41%)幸存者出现了复发性缩窄。这与手术年份相关,而与手术技术无关。对于主动脉缩窄的病例,当出现心力衰竭时,无论是否伴有心脏畸形,在3个月龄之前都不应推迟手术治疗。即使是单纯性缩窄(死亡率6%),手术修复良好后仍会出现猝死,再缩窄的发生率也很高,这表明对于3个月以下的婴儿,如果缩窄是单纯性的且耐受性良好,应考虑密切监测和保守药物治疗。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验