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麻疹疫苗的不良反应。

Adverse reactions to measles vaccine.

作者信息

Maspero A, Sesana B, Ferrante P

出版信息

Boll Ist Sieroter Milan. 1984 May 31;63(2):125-9.

PMID:6466453
Abstract

Adverse reactions to measles vaccine observed in children vaccinated between September, 1981 and May, 1983 in a Socio Sanitary Local Unit of Lombardy were studied. The adverse reactions more frequently reported by the parents were cough (18%), rash (12%), fever (9%), coryza (6%) and conjunctivitis (6%). Beginning September, 1982 a case-control study was started matching each vaccine with an unvaccinated child of the same age and sex. Statistically significant differences between vaccinated and controls have been observed only for rash and fever but not for the other symptoms. During the study febrile convulsions with spontaneous recovery and without sequelae have been observed in two vaccinated children.

摘要

对1981年9月至1983年5月在伦巴第一个社会卫生地方单位接种麻疹疫苗的儿童中观察到的不良反应进行了研究。家长报告的较常见不良反应有咳嗽(18%)、皮疹(12%)、发热(9%)、鼻炎(6%)和结膜炎(6%)。从1982年9月开始,开展了一项病例对照研究,将每名接种疫苗的儿童与一名年龄和性别相同的未接种疫苗儿童进行匹配。仅在皮疹和发热方面观察到接种疫苗儿童与对照儿童之间存在统计学显著差异,其他症状则未观察到差异。在研究期间,两名接种疫苗的儿童出现了热性惊厥,惊厥自行恢复且无后遗症。

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