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[Posttranslational deamidation of crystalline lens proteins during animal aging].

作者信息

Krichevskaia A A, Lukash A I, Pushkina N V, Shepotinovskaia I V, Sherstnev K B

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1984(7):23-8.

PMID:6466744
Abstract

The amide content of total proteins and protein fractions (alpha-, beta-, gamma-cristallins and albuminoid) from cortex and nuclear lens zones of cattle has been investigated. The amide content in proteins of cortex and nuclear lens of young animals (1,5-2 years old) is the same. The decrease of the amide content in the proteins of nuclear lenz zone of old animals (6-12 years old) is due to fraction of readily hydrolysed amides. The data obtained prove the posttranslational desamidation of lens proteins at ageing. beta-Cristallines--the proteins with the highest amides content is exposed to posttranslational desamidation most of all.

摘要

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