Teirlinck H C, Tangelder G J, Slaaf D W, Muijtjens A M, Arts T, Reneman R S
Biorheology. 1984;21(3):317-31. doi: 10.3233/bir-1984-21303.
Spatial orientation of blood platelets flowing in small arterioles of the rabbit mesentery was investigated using intravital fluorescence microscopy. Only platelets were studied that could be localized objectively within a thin optical section around the median plane of the vessel. The orientation of a platelet was assessed from its microscopic image and described by an angle pair, assuming the platelet to be an ellipsoidal body and using an empirical frequency distribution for its thickness to diameter ratio. The orientation of the platelets was not random; they tended to align themselves with their equatorial planes parallel to the wall. The degree of alignment increased from the center of the vessel toward the wall. As a corollary a frequency distribution of their diameter (3.15 +/- 0.72 micron (mean +/- sd) was obtained in vivo.
利用活体荧光显微镜研究了家兔肠系膜小动脉中流动的血小板的空间取向。仅研究了那些能够在血管中平面周围的薄光学切片内客观定位的血小板。根据血小板的显微图像评估其取向，并通过角度对进行描述，假设血小板为椭球体，并使用其厚度与直径比的经验频率分布。血小板的取向并非随机；它们倾向于使其赤道平面与血管壁平行排列。排列程度从血管中心向血管壁增加。作为一个推论，在体内获得了它们直径的频率分布（3.15±0.72微米（平均值±标准差））。
