Efuni S N, Kaplan E Ia, Lukash A I, Gukasov V M, Dudkin S I
Biull Eksp Biol Med. 1984 Jul;98(7):42-3.
The relative effectiveness of radical formation by different concentrations of hemoglobin, hemin and Fe2+ in the reaction with H2O2 evaluated by the intensity of chemiluminescence was studied. Hemoglobin was shown to be remarkably effective at the concentrations close to those in blood plasma. It is suggested that exoerythrocyte hemoglobin and the products of its destruction up to hemin are the most effective prooxidants and potential centers of radical formation in the blood.
通过化学发光强度评估了不同浓度的血红蛋白、血红素和Fe2+与H2O2反应形成自由基的相对有效性。结果表明,在接近血浆中的浓度时,血红蛋白具有显著的有效性。有人提出,红细胞外血红蛋白及其直至血红素的破坏产物是血液中最有效的促氧化剂和自由基形成的潜在中心。