Bell R A, Thompson H S
Arch Ophthalmol. 1978 Apr;96(4):638-42. doi: 10.1001/archopht.1978.03910050334008.
Ciliary muscle function in patients with Adie's syndrome was studied retrospectively in 122 patients and prospectively in 17 patients. When a careful history was taken, two thirds of the patients had ciliary muscle-related symptoms. Most of the patients with Adie's syndrome had a moderate accomodative paresis, but there was a strong tendency for the ciliary muscle to recover with time. Many patients showed a tonicity of accommodation, especially those who had had the condition for several years. Astigmatism could be induced with accommodation in one third of patients. This may be related to segmental paralysis of the ciliary muscle. Seventy-three percent of the patients showed supersensitivity of the ciliary muscle in the involved eye, when both eyes were treated with a mixture of 0.25% pilocarpine hydrochloride and hydroxypropyl methylcellulose (Isopto Carpine). This may be a clinical aid in diagnosing Adie's syndrome. Two patients were found to have bilateral ciliary muscle dysfunction but only unilateral pupillary abnormalities. These two patients may have had a "pupil-sparing" Adie's syndrome.
对122例阿-狄氏综合征患者的睫状肌功能进行了回顾性研究，并对17例患者进行了前瞻性研究。仔细询问病史时，三分之二的患者有与睫状肌相关的症状。大多数阿-狄氏综合征患者有中度调节麻痹，但睫状肌有随时间恢复的强烈趋势。许多患者表现出调节张力，尤其是患病数年的患者。三分之一的患者在调节时可诱发散光。这可能与睫状肌节段性麻痹有关。当双眼用0.25%盐酸毛果芸香碱和羟丙基甲基纤维素（爱普托品）混合液治疗时，73%的患者受累眼睫状肌表现为超敏反应。这可能是诊断阿-狄氏综合征的一项临床辅助手段。发现2例患者有双侧睫状肌功能障碍，但仅有单侧瞳孔异常。这2例患者可能患有“瞳孔保留型”阿-狄氏综合征。
