Arwood L L, Cordero L, Visconti J A
Dev Pharmacol Ther. 1984;7(4):259-62. doi: 10.1159/000457172.
The effect of intravenous (i.v.) tubing internal diameter and the position of the injection port on drug delivery were evaluated in an in vitro model. Two sets of i.v. tubing were compared and these were identical except for the diameter of the lumen. The large bone tubing took twice as long for the delivery of 95% of the drug compared to the small bore (120 and 60 min, respectively). In a separate study, identical (small bore) tubing was used to evaluate the effect of two injection port positions on drug delivery. The Y site injection port was placed with the injection hub pointing up or pointing down. Drug delivery times in these two specific positions were not statistically different.
在体外模型中评估了静脉输液管内径和注射端口位置对药物输送的影响。比较了两组静脉输液管，除管腔直径外，其他方面均相同。与小口径输液管相比，大口径输液管输送95%药物所需时间长两倍（分别为120分钟和60分钟）。在另一项研究中，使用相同的（小口径）输液管评估两个注射端口位置对药物输送的影响。Y型注射端口的注射接头朝上或朝下放置。这两个特定位置的药物输送时间在统计学上无差异。
