Rivero S J, Díaz-Jouanen E, Alarcón-Segovia D
Arthritis Rheum. 1978 Apr;21(3):295-305. doi: 10.1002/art.1780210302.
One hundred fifty-eight patients with active, untreated systemic lupus erythematosus (SLE) were studied from the time of diagnosis. Lymphopenia was present in 75%, and another 18% of those patients developed lymphopenia subsequent to disease reactivation. Lymphopenia of less than 1500 cells/microliter occurred more frequently than any of the preliminary criteria for the classification of SLE, and it was the most prevalent initial laboratory abnormality. Lymphocyte counts were significantly lower in lupus than in the other connective tissue diseases except mixed connective tissue disease and polymyositis.
自诊断之时起，对158例未经治疗的活动性系统性红斑狼疮（SLE）患者进行了研究。75%的患者存在淋巴细胞减少，另有18%的患者在疾病复发后出现淋巴细胞减少。低于1500个细胞/微升的淋巴细胞减少比SLE分类的任何一项初步标准出现得都更频繁，且是最常见的初始实验室异常。除混合性结缔组织病和多发性肌炎外，狼疮患者的淋巴细胞计数显著低于其他结缔组织病。
