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[蛛网膜下腔出血相关的心律失常。动态心电图的前瞻性研究]

[Cardiac arrhythmias associated with subarachnoid hemorrhage. Prospective study with dynamic electrocardiography].

作者信息

Di Pasquale G, Lusa A M, Manini G L, Dominici P, Andreoli A, Limoni P, Pinelli G

出版信息

G Ital Cardiol. 1984 May;14(5):323-9.

PMID:6468812
Abstract

Electrocardiographic abnormalities associated with intracranial diseases, especially subarachnoid hemorrhage, are well known, while there is hardly mention of cardiac arrhythmias in the neurological and cardiological literature. In order to assess the incidence of arrhythmias 52 consecutive patients with subarachnoid hemorrhage secondary to ruptured aneurysm were investigated with 24-hour Holter recordings. Bradyarrhythmias and tachyarrhythmias were found in 46 patients (88%); premature ventricular beats in 25 pts (12 of these in 3rd-5th Lown classes), ventricular tachycardia in 2, premature supraventricular beats in 14, paroxysmal atrial fibrillation in 1, sinoatrial blocks and arrests in 18, atrioventricular dissociation in 2 and idioventricular rythm in 2. Moreover in 5 pts ST segment changes were found, suggestive of transitory acute myocardial ischemia. The presence and severity of arrhythmias were correlated with the time elapsed from the episode of bleeding, with the QT interval, and with the hemorrhage extent. Our results indicate an high incidence of arrhythmias in subarachnoid hemorrhage, sometimes serious mainly in early stage. Continuous electrocardiographic monitoring is therefore extremely useful and provides data for therapeutic consideration.

摘要

颅内疾病,尤其是蛛网膜下腔出血所伴发的心电图异常已为人熟知,然而神经学和心脏病学文献中却很少提及心律失常。为评估心律失常的发生率,我们对52例因动脉瘤破裂继发蛛网膜下腔出血的连续病例进行了24小时动态心电图记录研究。结果发现,46例患者(88%)出现了缓慢性心律失常和快速性心律失常;25例患者出现室性早搏(其中12例为洛恩3 - 5级),2例出现室性心动过速,14例出现室上性早搏,1例出现阵发性心房颤动,18例出现窦房阻滞和停搏,2例出现房室分离,2例出现心室自主节律。此外,5例患者出现ST段改变,提示短暂性急性心肌缺血。心律失常的存在及严重程度与出血发生后的时间、QT间期以及出血范围相关。我们的结果表明,蛛网膜下腔出血时心律失常的发生率很高,有时在早期较为严重。因此,持续的心电图监测极为有用,并可为治疗提供参考依据。

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