Vargas Origel A, Cetina Sauri G, Lima Dávila G, Rodríguez Cueto G, Jasso Gutiérrez L
Bol Med Hosp Infant Mex. 1978 Jul-Aug;35(4):679-86.
The study included 17 cases of osteomyelitis in the newborn period, admitted through a period of 10 years. Males showed a rate of 1.8:1 over females. The possible port of entry was established in 11 cases. The most important clinical signs were: edema, erythema, hypomotility and fluctuation. In one third of the cases, systemic infection signs were eident and in 4 cases, confirmation resulted from blood cultures positive to gram-negative germs. The germ most frequently isolated in the secretion was S. aureus, followed by Klebsiella. The analysis included the pathogenesis that explains the high percentage of articular participation (65%) and the presence of multiple foci which, together with other characteristics, make osteomyelitis at this age, different from that seen during other stages of life in terms of diagnosis, management and prognosis.
该研究纳入了10年间收治的17例新生儿期骨髓炎病例。男性与女性的比例为1.8:1。11例确定了可能的感染入口。最重要的临床体征为：水肿、红斑、活动减少和波动感。三分之一的病例有全身感染体征，4例血培养革兰氏阴性菌阳性得以确诊。分泌物中最常分离出的细菌是金黄色葡萄球菌，其次是克雷伯菌。分析内容包括解释关节受累比例高（65%）和多病灶存在的发病机制，这些与其他特征一起，使得这个年龄段的骨髓炎在诊断、治疗和预后方面与生命其他阶段所见的骨髓炎有所不同。
