Page R E, Deverall P B, Watson D A, Scott O
Br Heart J. 1978 Apr;40(4):416-20. doi: 10.1136/hrt.40.4.416.
In a consecutive series of 100 cases of Fallot's tetralogy undergoing total correction, the mean birthweight was found to be just below the 50th centile. Blalock-Taussig or Waterston shunts were performed in 45 patients. Before their shunt operations a significant number of patients had become retarded in height and weight development but after the shunt operations many patients showed accelerated height and weight gain. Of the 73 patients followed up 2 years after correction, 23 had experienced accelerated development in both weight and height, but 11 patients remained on or below the 3rd centile for weight and height. In terms of the age at shunting, the oxygen saturation immediately before total correction, the age at total correction, the number of ventriculotomy patch repairs, and the post-correction ventricular pressure ratios, no significant difference could be detected between those 23 patients who had undergone accelerated development and those 11 who had remained retarded. More shunts, particularly of the Waterston type, were performed in the retarded group.
在连续100例接受根治手术的法洛四联症患者中,平均出生体重略低于第50百分位数。45例患者进行了锁骨下动脉-肺动脉吻合术(Blalock-Taussig分流术)或升主动脉-肺动脉吻合术(Waterston分流术)。在进行分流手术前,相当多的患者身高和体重发育迟缓,但分流手术后,许多患者身高和体重增加加速。在73例根治术后随访2年的患者中,23例体重和身高均加速发育,但11例患者体重和身高仍处于或低于第3百分位数。就分流时的年龄、根治术前即刻的血氧饱和度、根治时的年龄、心室切开补片修复的次数以及根治术后心室压力比值而言,在23例加速发育的患者与11例发育迟缓的患者之间未检测到显著差异。发育迟缓组进行了更多的分流手术,尤其是Waterston分流术。