产生促红细胞生成素的男性化恶性脂质细胞瘤。

Virilizing malignant lipid cell tumor producing erythropoietin.

作者信息

Montag T W, Murphy R E, Belinson J L

出版信息

Gynecol Oncol. 1984 Sep;19(1):98-103. doi: 10.1016/0090-8258(84)90164-1.

Abstract

Paraneoplastic erythrocytosis associated with production of erythropoietin and testosterone by a malignant lipid cell tumor is demonstrated in this case report. Several chemotherapeutic regimens failed to halt the progression of this aggressive metastatic lipid cell tumor. The scant literature on malignant lipid cell tumors is reviewed. Possible mechanisms for paraneoplastic erythrocytosis are presented. Adequate control of polycythemia preoperatively will reduce thromboembolic and hemorrhagic complications.

摘要

本病例报告展示了与恶性脂质细胞瘤产生促红细胞生成素和睾酮相关的副肿瘤性红细胞增多症。几种化疗方案未能阻止这种侵袭性转移性脂质细胞瘤的进展。本文回顾了关于恶性脂质细胞瘤的少量文献。提出了副肿瘤性红细胞增多症的可能机制。术前充分控制红细胞增多症将减少血栓栓塞和出血并发症。