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两种小鼠t单倍型（tw12tf和tLub-1）之间的重组：H-2复合体相对于着丝粒和簇状（tf）基因座的定位。

Recombination between two mouse t haplotypes (tw12tf and tLub-1): mapping of the H-2 complex relative to centromere and tufted (tf) locus.

作者信息

Pla M, Condamine H

出版信息

Immunogenetics. 1984;20(3):277-85. doi: 10.1007/BF00364209.

DOI:10.1007/BF00364209
PMID:6469289
Abstract

A monoclonal antibody known to recognize the H-2.m3 specificity is shown to react with the class I H-2 product of tLub-1 but not tw12tf mice. This reagent was used to study the segregation of the H-2 complex in the progeny of tLub-1 +/tw12tf females. The most straightforward interpretation of the results presented here is that these t haplotypes carry an H-2 complex located between the centromere and tufted locus. Possible consequences of such a location with regard to the recombination between t haplotypes and chromosome 17 from laboratory mice are discussed.

摘要

已知一种识别H-2.m3特异性的单克隆抗体可与tLub-1小鼠的I类H-2产物发生反应，但不与tw12tf小鼠的I类H-2产物发生反应。该试剂用于研究tLub-1 +/tw12tf雌性小鼠后代中H-2复合体的分离情况。此处呈现结果的最直接解释是，这些t单倍型携带一个位于着丝粒和簇状位点之间的H-2复合体。讨论了这种位置对于t单倍型与实验室小鼠17号染色体之间重组的可能影响。

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Immunogenetics. 1984;20(3):277-85. doi: 10.1007/BF00364209.
2
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T(16: 17)43H translocation as a tool in analysis of the proximal part of chromosome 17 (including T-t gene complex) of the mouse.T(16:17)43H易位作为分析小鼠17号染色体近端部分（包括T-t基因复合体）的一种工具。
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Recombination between two mouse t-haplotypes (tw12tf and tLub-1): segregation of lethal factors relative to centromere and tufted (tf) locus.
Genet Res. 1983 Dec;42(3):335-44. doi: 10.1017/s0016672300021819.
9
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Linkage disequilibrium between H-2 and t complexes in chromosome 17 of the mouse.小鼠17号染色体上H-2与t复合体之间的连锁不平衡。
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