Breuninger H, Rassner G, Undeutsch W
Hautarzt. 1984 Jun;35(6):303-7.
An integrated concept for the surgical treatment of basal cell carcinoma is presented, which is based on individually calculated safety margins and modified microscopically controlled surgery. The individual calculation of the safety margin assumes there is a relationship between the clinically visible tumor diameter and subclinical infiltration; the calculation of the safety margin therefore is based on the size of the clinically visible portion of the basal cell carcinoma. Detection of subclinical infiltration and exclusion of the possibility of subtotal excision are ensured by routine histological control of the margins of the excised specimen. The surgical treatment of basal cell carcinoma presented in this study is considerably less time-consuming than other forms of microscopically controlled surgery. No recurrences have been observed after radical excision of basal cell carcinomas with this method.
本文提出了一种基底细胞癌手术治疗的综合概念，该概念基于个体化计算的安全切缘和改良的显微镜控制手术。安全切缘的个体化计算假设临床可见肿瘤直径与亚临床浸润之间存在关联；因此，安全切缘的计算基于基底细胞癌临床可见部分的大小。通过对切除标本边缘进行常规组织学检查，确保亚临床浸润的检测以及排除不完全切除的可能性。本研究中提出的基底细胞癌手术治疗比其他形式的显微镜控制手术耗时显著更少。采用这种方法对基底细胞癌进行根治性切除后未观察到复发情况。
